Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex
Damage and disease of nerves activates the complement system.We demonstrated that activation of the terminal pathway of the complement system leads to the formation of the membrane attack complex (MAC) and delays regeneration Pump in the peripheral nervous system.Animals deficient in the complement component C6 showed improved recovery after neuron